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4000-520-616 / 18915418616
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0512-67156496
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商品描述
OVERVIEW:
Synonyms | Monoclonal CENPH antibody, Anti-CENPH antibody, NNF1 antibody, PMF1 antibody,PMF1 antibody, NNF1, MIND kinetochore complex component, homolog antibody, kinetochore protein CENP-H antibody, centromere protein H antibody |
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Cross Reactivity | Human |
Applications | WB |
Immunogen | CENPH antibody was raised in Mouse using full length human recombinant protein of human CENPH produced in HEK293T cell as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 1C2 |
Isotype | IgG1 |
Method of Purification | CENPH antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5-1 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
Usage Recommendations | WB: 1:2000 |
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GENERAL INFORMATION:
Biological Significance | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. |
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