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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
OVERVIEW:
Synonyms | MonoclonalAKT1antibody,Anti-AKT1antibody,AKTantibody,MGC99656antibody,PKBantibody,PKB-ALPHAantibody,PRKBAantibody,RACantibody,RAC-ALPHAantibody,AKT1,AKT1,AKT-1,AKT1antibody,AKT-1antibody |
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CrossReactivity | Human,Dog,Rat,Monkey,Mouse |
Applications | FC,IF,IHC,WB |
Immunogen | AKT1antibodywasraisedinMouseusingfulllengthhumanrecombinantproteinofhumanAKT1producedinHEK293Tcellastheimmunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 3B4 |
Isotype | IgG1 |
MethodofPurification | AKT1antibodywaspurifiedbyaffinitychromatography. |
Form&Buffer | SuppliedinPBSbuffer,pH7.3,containing1%BSA,50%glyceroland0.02%sodiumazide. |
Concentration | 0.5-1mg/ml |
STORAGE&SAFETY:
Storage | Storeat4degCforshorttermstorage.Aliquotandstoreat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles. |
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UsageAssayInformation:
UsageRecommendations | IF:1:100,FC:1:100,IHC:1:150,WB:1:500-2000 |
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GENERALINFORMATION:
BIOLOGicalSignificance | Theserine-threonineproteinkinaseAKT1iscatalyticallyinactiveinserum-starvedprimaryandimmortalizedfibroblasts.AKT1andtherelatedAKT2areactivatedbyplatelet-derivedgrowthfactor.Theactivationisrapidandspecific,anditisabrogatedbymutationsinthepleckstrinhomologydomainofAKT1.Itwasshownthattheactivationoccursthroughphosphatidylinositol3-kinase.InthedevelopingnervoussystemAKTisacriticalmediatorofgrowthfactor-inducedneuronalsurvival. |
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