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苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
OVERVIEW:
Synonyms | Monoclonal PSMB4 antibody, Anti-PSMB4 antibody, Proteasome macropain subunit beta type 4 antibody ,Prosome Macropain Subunit Beta Type 4 antibody, HN3 antibody, HsN3 antibody, PROS26 antibody, PSMB4, PSMB 4, PSMB-4, PSMB 4 antibody, PSMB-4 antibody |
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Cross Reactivity | Human |
Applications | IHC, WB |
Immunogen | PSMB4 antibody was raised in mouse using a full length recombinant protein of human PSMB4 (NP_002787) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 2C9 |
Isotype | IgG1 |
Method of Purification | PSMB4 antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
Usage Recommendations | IHC: 1:150, WB: 1:2000 |
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GENERAL INFORMATION:
Biological Significance | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB4 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. |
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