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商品描述
OVERVIEW:
Synonyms | Monoclonal KHK antibody, Anti-KHK antibody, Ketohexokinase antibody, Fructokinase antibody, Monoclonal KHK antibody, Anti-KHK antibody, Ketohexokinase antibody, Fructokinase antibody |
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Cross Reactivity | Human |
Applications | FC, IHC |
Immunogen | KHK antibody was raised in mouse using a full length recombinant protein of human KHK (NP_000212) produced in HEK293T cells, as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 3C4 |
Isotype | IgG1 |
Method of Purification | KHK antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
Usage Recommendations | FC: 1:100, IHC: 1:50, WB: 1:2000 |
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GENERAL INFORMATION:
Biological Significance | KHK is a ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. KHK encodes the gene ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The splice variant presented encodes the highly active form found in liver, renal cortex, and small intestine, while the alternate variant encodes the lower activity form found in most other tissues. |
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