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苏州工业园区生物纳米园A4#216
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商品描述
OVERVIEW:
| Synonyms | MonoclonalS100antibody,Anti-S100antibody,S100AstrocyteMarker,S100,S-100antibody,S100antibody,S100,S-100antibody,S100Proteinantibody,S-100 |
|---|---|
| Specificity | Bovine |
| CrossReactivity | Human |
| Applications | IHC,WB |
| Immunogen | S100antibodywasraisedinmouseusingbovinebrainS100proteinastheimmunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 2A10 |
| Isotype | IgG1 |
| Purity | Culturesupernatant |
| MethodofPurification | S100antibodywaspurifiedwithproteinA |
| Form&Buffer | Lyophilizedproductfrom1%BSAinPBScontaining0.05%NaN3,reconstitutewith1mlofdistilledwater |
STORAGE&SAFETY:
| Storage | Storeat4degCuntilreconstitution.Followingreconstitutionaliquotandfreezeat20degCforlongtermstorage |
|---|
UsageAssayInformation:
| UsageRecommendations | IHC:25ug/ml,WB:25ug/ml |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | S100proteins(16members)showaverydivergentpatternofcellandtissuespecificexpression,ofsubcellularlocalizationsandrelocations,ofposttranslationalmodifications,andofaffinitiesforCa2+,Zn2+,andCu2+,consistentwiththeirpleiotropicintraandextracellularfunctions.Upto40targetproteinsarereportedtointeractwithS100proteinsandforS100A1alone15targetproteinsarepresentlyknown.Thereforeitisnotsurprisingthatmanyfunctionalroleshavebeenproposedandthatseveralhumandisorderssuchascancer,neurodegenerativediseases,cardiomyopathies,inflammations,diabetes,andallergiesareassociatedwithanalteredexpressionofS100proteins. |
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