OVERVIEW:

Synonyms	Monoclonal AAV Replicase antibody, Anti-AAV Replicase antibody, Adeno Associated Virus Replicase antibody
Specificity	AAV Replicase
Cross Reactivity	Monkey
Applications	IF, IP
Immunogen	AAV Rep protein antibody was raised in mouse using recombinant AAV-2 Rep78 protein as the immunogen.

SPECIFICATIONS:

Host	Mouse
Clone	76.5
Isotype	IgG1
Form & Buffer	Supplied in liquid form, contains 0.01% Thimerosal

STORAGE & SAFETY:

Storage	Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations	Optimal conditions to be determined by end user

GENERAL INFORMATION:

Biological Significance

Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models.

Fitzgerald免疫球蛋白是由B细胞产生的大的Y形蛋白质，被免疫系统用来识别和中和细菌和病毒等异物。免疫球蛋白识别每种抗原的独特部分。Y形的每个尖端均靶向外源抗原上的一个表位，从而使两个分子能够以极高的精度结合。使用这种结合机制，抗体可以识别并标记微生物或另一种受感染的细胞，以便受到免疫系统的攻击，或者在某些情况下，通过结合并阻断其一个或多个过程来中和靶标本身。免疫球蛋白的产生是体液免疫系统的主要功能，基于结构和抗原特性有五种不同的类别：IgA，IgD，IgE，IgG和IgM。如果您正在寻找高纯度的产品，高质量的免疫球蛋白及其相关同种型，可用于医学或工业诊断和研究，血清学，ELISA，蛋白质印迹，免疫荧光和其他免疫分析，然后Fitzgerald Industries提供了广泛的免疫球蛋白，可供选择的各种禽类和哺乳动物宿主物种出售。除了五个主要免疫球蛋白类别的纯化效价外，菲茨杰拉德还提供完整的α，β和γIg同种型，异硫氰酸荧光素（FITC），辣根过氧化物酶（HRP）和生物素结合的免疫球蛋白，Fc特异性，Fab和Fab2片段以及也可以提供来自多个宿主物种的重链，轻链，γ和λ链。我们的免疫球蛋白可根据要求与大量宿主一起批量购买或滴定度更小，目标和共轭物，以满足您的需求。我们的免疫球蛋白和抗体范围不断更新，并带有新的靶标，因此请随时与我们联系，以了解您的具体要求。