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0512-67156496
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商品描述
OVERVIEW:
Synonyms | Monoclonal PPP1R13L antibody, Anti-PPP1R13L antibody, iASPP gene antibody, NKIP1 antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 13 like antibody, PPP1R13L, PPPR3L 1, RAI antibody, IASPP antibody, PPPR3L-1 antibody, PPPR3L 1 antibody, PPPR3L-1 |
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Specificity | Human PPP1R13L |
Cross Reactivity | Human. Other species not studied |
Applications | Dot Blot, ICC, WB |
Immunogen | PPP1R13L antibody was raised in mouse using recombinant Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 13 Like (Ppp1R13L) |
SPECIFICATIONS:
Host | Mouse |
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Clone | 2808C5a |
Isotype | IgG1 |
Method of Purification | PPP1R13L antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. |
Form & Buffer | PPP1R13L antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ). |
Concentration | 100 ug/ml |
STORAGE & SAFETY:
Storage | Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing. |
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Biohazard Information | This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv |
Usage Assay Information:
Usage Recommendations | WB: 0.2-2 ug/ml |
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GENERAL INFORMATION:
Biological Significance | PPP1R13L is a regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. It also blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis{EC1,EC2,EC3,EC4}. |
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