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商品描述
OVERVIEW:
Synonyms | Monoclonal Cytokeratin 20 antibody, Anti-Cytokeratin 20 antibody, Cytokeratin 20, Cytokeratin 20 antibody, Cytokeratin -20, Cytokeratin -20 antibody, Keratin K20 antibody, Cytokeratin 20 |
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Specificity | Human cytokeratin 20 |
Cross Reactivity | Human, mouse, pig, rat |
Applications | ELISA, IHC-F, IHC-P, WB |
Immunogen | Cytokeratin 20 antibody was raised in mouse using electrophoretically purified cytokeratin 20 from human intestinal mucosa as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | IT-Ks20.10 |
Isotype | IgG1 |
Method of Purification | Protein A affinity chromatography |
Form & Buffer | Supplied as a lyophilized powder. Reconstitute in 1 ml dist. water (final solution contains 0.09 % NaN3, 0.5% BSA in PBS buffer, pH 7.4) |
STORAGE & SAFETY:
Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles. |
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Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
Usage Assay Information:
Usage Recommendations | IHC-F: 1:10 |
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GENERAL INFORMATION:
Biological Significance | Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin 20, often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. |
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