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商品描述
OVERVIEW:
Synonyms | Monoclonal Cytokeratin 7 antibody, Anti-Cytokeratin 7 antibody, Keratin K7 antibody, Cytokeratin -7, Cytokeratin 7, Cytokeratin 7, Cytokeratin -7 antibody, Cytokeratin 7 antibody |
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Specificity | Human cytokeratin 18 |
Cross Reactivity | Bovine, human, pig, sheep |
Applications | IHC-F, WB |
Immunogen | Cytokeratin 7 antibody was raised in mouse using cytoskeletal proteins from cultured HeLa cells as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | Ks7.18 |
Isotype | IgG1 |
Method of Purification | Protein A affinity chromatography |
Form & Buffer | Lyophilized from a solution containing 0.5% BSA and 0.09% NaN3. Reconstitute with 1ml of distilled water. |
STORAGE & SAFETY:
Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles. |
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Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
Usage Assay Information:
Usage Recommendations | IHC-F: 1:50 |
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GENERAL INFORMATION:
Biological Significance | Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin, type I cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene. Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. |
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