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商品描述
SGC707
1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
Potent and selective allosteric inhibitor of proteinarginine methyltransferase 3 (PRMT3)1. IC50 = 31 nM and selective against 31 othermethyltransferases. An extremely useful probe for investigating the role ofPRMT3 in normal and pathophysiology. Cell permeable and active in vivo.
Physical Properties:Beige crystallinepowder; MP=233-235°C
MW=298.3 C16H18N4O2
Solubilization:May be dissolvedin DMSO (35 mg/ml)
Storage:Store desiccated assupplied at -20°C for up to 2 years. Store solutions at -20°C for up to 3 months.
Amount: 5 mg
