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蚂蚁淘在线 / 品牌中心 / Reaction Biology / Reaction Biology/UNC-2170/EI-MTL-001

Reaction Biology/UNC-2170/EI-MTL-001

价格
￥1740.00
货号：EI-MTL-001
浏览量：81
品牌：Reaction Biology
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商品描述

UNC-2170

3-Bromo-N-(3-(tert-butylamino)propyl)benzamide,hydrochloride

TheDNAdamageresponseprotein53BP1utilizesitstandemtudordomaintorecognizedimethylatedlysine20onhistone(H4K20me2),amodificationassociatedwithdouble-strandDNAbreaks.UNC-2170,identifiedbyscreening,wasfoundtobeauMligandfor53BP1whichalsodemonstratedatleast17-foldselectivityfor53BP1overothermethyllysinebindingproteins.Thecompoundfunctionsasa53BP1antagoNISTincelllysatesandsuppressesclassswitchrecombinationinwholecells,aprocessrequiringafunctioning53BP1tudordomain.

PhysicalProperties:Whitepowder

MW=349.7C14H21BrN2O•HCl

Analysis:>98%(TLC);NMR(Conforms)

Solubilization:MaybedissolvedinDMSO(40mg/ml);orwater(50mg/ml)

Storage:Storedesiccatedassuppliedat-20°Cforupto2years.Storesolutionsat-20°Cforupto3months.

Amount:5mg

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