品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
AK-7 
Reaction Biology常用产品报价单产品名货号公司分类商城分类美金价Reaction Biology/ASH1L (His) Methyltransferase/HMT-11-376HMT-11-376Biochemical Assay Services反应底物375.00Reaction Biology/Core Histones (Chicken)/HMT-35-435HMT-35-435Biochemical Assay Services抗鸡290.00Reaction Biology/BromoMELT Assay Kit/BRD-Kit-01BRD-Kit-01Cell AssaysRACE试剂盒920.00Reaction Biology/NDS2 Protein/HMT-21-122HMT-21-122Electrophysiology Assays蛋白纯化试剂盒635.00Reaction Biology/NSD2 (His) Methyltransferase Protein/HMT-21-138HMT-21-138Electrophysiology Assays细胞因子520.00Reaction Biology/MPP8-[CHR] (His) {M-phase phosphoprotein 8-[CHR] (His)}/RD-11-462RD-11-462Electrophysiology Assays血清纯化蛋白320.00Reaction Biology/PRMT5 Methyltransferase Protein - Buy Online Now/HMT-22-148HMT-22-148Electrophysiology Assays生长因子925.00 3-(1-Azepanylsulfonyl)-N-(3-bromophenyl)benzamide
AK-7 is a selective Sirt2 inhibitor (IC50=15.5 mM) which does not inhibit Sirt1 orSirt3. It down-regulates cholesterol biosynthesis genes in primarystriatal neurons. Displays neuroprotective effects in Huntington’sdisease mouse models including improved motor function, extended survival andreduced brain atrophy all of which were associated with reduced aggregatedmutant huntingtin.Physical Properties: White powder;MP=148-151°C
MW=437.4 C19H21BrN2O3S
Analysis: 98%(TLC); NMR (Conforms)
Solubilization: May be dissolved in DMSO (50 mg/ml); or ethanol (8 mg/ml,warm)
Storage: Store desiccated assupplied at ambient temperature for up to 3 years. Store solutions at -20°C forup to 3 months.
Amount: 5mg
