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商品描述
EX-527 
Reaction Biology常用产品报价单产品名货号公司分类商城分类美金价Reaction Biology/ASH1L (His) Methyltransferase/HMT-11-376HMT-11-376Biochemical Assay Services反应底物375.00Reaction Biology/Core Histones (Chicken)/HMT-35-435HMT-35-435Biochemical Assay Services抗鸡290.00Reaction Biology/BromoMELT Assay Kit/BRD-Kit-01BRD-Kit-01Cell AssaysRACE试剂盒920.00Reaction Biology/NDS2 Protein/HMT-21-122HMT-21-122Electrophysiology Assays蛋白纯化试剂盒635.00Reaction Biology/NSD2 (His) Methyltransferase Protein/HMT-21-138HMT-21-138Electrophysiology Assays细胞因子520.00Reaction Biology/MPP8-[CHR] (His) {M-phase phosphoprotein 8-[CHR] (His)}/RD-11-462RD-11-462Electrophysiology Assays血清纯化蛋白320.00Reaction Biology/PRMT5 Methyltransferase Protein - Buy Online Now/HMT-22-148HMT-22-148Electrophysiology Assays生长因子925.00 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide(racemic)
EX-427 is a selective Sirt1 inhibitor (IC50=98nM). Does not inhibit other HDACs or Sirt family members. Increases p53acetylation following DNA damage. Causes cell cycle arrest at G1.Inhibits differentiation and facilitatesexpansion of hematopoietic progenitor cells. An extremely usefultool for determining the involvement of Sirt1 in cellular physiology.Cell permeable.Physical Properties: Light yellow powder
MW=248.7 C13H13ClN2O
Analysis: >98% (TLC); NMR (Conforms)
Solubilization: May be dissolvedin DMSO (18 mg/ml); or Ethanol (10 mg/ml)
Storage: Store desiccated as supplied at 4°C for up to2 years. Store solutions at -20°C for up to 2 months.
