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蚂蚁淘在线 / 品牌中心 / Adipogen / Adipogen/CD40L [CD154] (human)-muCD8 Fusion Protein (Biotin)/ANC-505-030/25 µg
商品描述
| ProductDetails | |
|---|---|
| ProductType | Protein |
| Properties | |
| Source/Host | CHOcells |
| Application | FlowCytometry ELISA WesternBlot |
| Label/Conjugates | Biotin |
| Formulation | 50mMSodiumPhosphatepH7.5,100mMPotassiumChloride,150mMNaCl,5%Glycerol,0.2%BSA,0.04%NaN3(asapreservative). |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAncellCorporation. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
HumanCD154(CD40ligand)isamemberoftheTNFfamilyandisexpressedonthesurfaceofactivatedTcells.Itcanundergoproteolyticcleavageintoa19kDaimmunologicallyactivesolubleform.InteractionofCD154andCD40isessentialforisotypeswitchinginBcells.Knowngeneticdefectsthatalterthisinteractionleadtoimpairedimmunesystemfunction.IncreasedlevelsofCD154hasbeenassociatedwithautoimmunedisordersincludingSLE,CLLandeosinophilicfasciitis.CD154hasbeenreportedtobeexpressedonvascularendothelialcells,smoothmusclecells,macrophagesandactivatedplateletsindicatingarolefortheCD40-CD154immunoregulatorysignalinginartherosclerosisandcardiovasculardisorders.
