品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
| ProductDetails | |
|---|---|
| Synonyms | CollagenTripleHelixRepeat-containingProtein1;NMTC1 |
| ProductType | Protein |
| Properties | |
| Source/Host | CHOcells |
| Sequence | MouseCTHRC1(aa33-245)isfusedattheN-terminustoaFLAG®-tag. |
| Crossreactivity | Mouse |
| MW | ~Twobandsof25-30kDa(SDS-PAGE) |
| Purity | ≥90%(SDS-PAGE) |
| EndotoxinContent | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 0.1mg/mlafterreconstitution. |
| Reconstitution | Reconstitutewith100μlsterilewater. |
| Formulation | Lyophilized.ContainsPBS. |
| OtherProductData | UniProtlinkQ9D1D6:CTHRC1(mouse) FLAGisaregisteredtrademarkofSigma-AldrichCo. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Collagentriplehelixrepeatcontaining-1(CTHRC1)isa30kDaglycosylatedsecretoryproteincontainingashortcollagen-likemotifcontributingtovascularremodelingbylimitingcollagenmatrixdepositionandpromotingcellmigration.CTHRC1isexpressedincalcifiedatheroscleroticplaqueandchondrocyte-likecells,inthehypothalamus,pituitaryglandandremodelingtissues.AberrantexpressionofCTHRC1ispresentinhumansolidcancersandlikelytobeassociatedwithcancerinvasionandmetastasis.WithADIponectinandothermembersoftheC1q/TNF-relatedprotein(Ctrp)family,CTHRC1sharesthepresenceofashortN-terminalcollagendomainbutitlacksthecharacteristicC1qdomainthatdefinestheCTRPfamilyofproteins.ArecentstudyidentifiesCTHRC1asanovelcirculatinghormonewithmetaboliceffects.
