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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
ProductDetails | |
---|---|
ProductType | Chemical |
Properties | |
Formulation | Liquid. |
Crossreactivity | Multi-species |
Declaration | ManufacturedbyBostonBiochem |
OtherProductData | Use:HSPReactionBufferisformulatedtosupporttheinvitroenzymaticactivityofheatshockproteins.Thisbufferissimilarincompositionto10XE3LigaseReactionBuffer,butcontainspotassiumchloridethatimprovesthecatalyticfunctionofHSP70invitro.FullycompatIBLewithE1,E2,andE3ubiquitinligaseenzymeactivities,thisbuffercanbeusedforinvitroproteinrefoldingexperiments,orinubiquitinationreactionsthatrequireHSPactivity.ThisbufferdoesnotcontainMg2+-ATP.Diluteto1Xinfinalreaction. |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | DownloadPDF |
ProductSpecificationSheet | |
Datasheet | DownloadPDF |
Theheatshockproteinsareahighlyconservedfamilyofstressresponseproteins.HSPsfunctionprimarilyasmolecularchaperones,facilitatingthefoldingofothercellularproteins,preventingproteinaggregation,ortargetingimproperlyfoldedproteinstospecificdegradativepathways.SomeHSPsareexpressedatlowlevelsundernormalphysiologicalconditionsbutshowdramaticallyincreasedexpressioninresponsetocellularstress,othersareconstitutivelyexpressed.SpecificHSPsplayaroleinregulatingcancerbyinteractingdirectlywithkeycomponentsoftheapoptoticpathway.