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商品描述
| ProductDetails | |
|---|---|
| Synonyms | Interleukin-2;Aldesleukin |
| ProductType | Protein |
| Properties | |
| Source/Host | CHOcells |
| Sequence | TheextracellulardomainofhumanIL-2(aa21-153)isfusedtotheN-terminusoftheFcregionofhumanIgG1. |
| Crossreactivity | Human |
| Purity | ≥98%(SDS-PAGE) |
| EndotoxinContent | <0.06eu mu;g="" protein="" (lal="" test;="" lonza).=""> |
| Reconstitution | Reconstitute50µgvialin50µlsterilewater. Add1XPBStothedesiredproteinconcentration. |
| Formulation | Lyophilizedfrom0.2μm-filteredsolutioninPBS. |
| OtherProductData | NCBIreferenceNP_000577.2:IL-2(human) |
| Declaration | ManufacturedbyChimerigen. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Interleukin-2(IL-2)isa133aminoacidglycoproteinwithoneintramoleculardisulfidebondandvariableglycosylation.ItissecretedbyactivatedTcellsandinducesproliferationandmaturationofactivatedTcells,naturalkillercells,andlymphokineactivatedkillercells.IL-2alsostimulatesproliferationofantibody-producingBcells,activatesneutrophils,andinducesmononuclearcellstosecreteIFN-γandTNF-αand-β.Moreover,studieshaveshownthatIL-2isrequiredforactivation-inducedapoptosis,animportanthemeostaticmechanismintheimmunesystem,whichisinvolvedinthemaintenanceofperipheraltolerancetoself-antigens.
