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蚂蚁淘在线 / 品牌中心 / Adipogen / Adipogen/Transthyretin (Prealbumin) (human) ELISA Kit (20x96T)/YIF-LF-EK0184/20 x 96 wells
商品描述
| ProductDetails | |
|---|---|
| Synonyms | TTR;PALB;TBPA;ATTR;Prealbumin;Transthyretin |
| ProductType | Kit |
| Properties | |
| ApplicationSet | CompoundScreening |
| Crossreactivity | Human |
| Quantity | 20x96wells |
| Sensitivity | 0.24ng/ml |
| AssayType | Sandwich |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Anyunusedreconstitutedstandardshouldbediscardedorfrozenat-80℃. Standardcanbefrozenandthawedonetimeonlywithoutlossofimmunoreactivity. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Transthyretin(TTR,55kDahomotetramer)isathyroidhormone-bindingproteinthattransportsthyroxine(T4)fromthebloodstreamtothebrain.TTRwasoriginallycalledprealbuminbecauseitranfasterthanalbuminonelectrophoresisgels.TTRisproducedintheliverandcirculatesinthebloodstream,whereitbindsretinolandthyroxine.TTRissuggestedthatplaysanessentialroleinbrainfunction.Theproteinconsistsofaround130aminoacids,whichassembleasahomotetramerthatcontainsaninternalchannelinwhichT4isbound.Withinthiscomplex,T4appearstobetransportedacrosstheblood-brainbarrier,where,inthechoroidplexus,thehormonestimulatesfurthersynthesisoftransthyretin.Theproteinthendiffusesbackintothebloodstream,whereitbindsT4fortransportbacktothebrain.TTRisknowntobeassociatedwiththeamyloiddiseasessenilesystemicamyloidosis(SSA),familialamyloidpolyneuropathy(FAP),andfamilialamyloidcardiomyopathy(FAC).Thyroidhormone-bindingprotein.Probablytransportsthyroxinefromthebloodstreamtothebrain.
