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蚂蚁淘在线 / 品牌中心 / Adipogen / Adipogen/Superoxide Dismutase 4 (SOD4) (human) ELISA Kit (4x96T)/YIF-LF-EK0210/4 x 96 wells
商品描述
| ProductDetails | |
|---|---|
| Synonyms | CCS;SuperoxideDismutaseCopperChaperone;CopperChaperoneforSuperoxideDismutase |
| ProductType | Kit |
| Properties | |
| ApplicationSet | CompoundScreening |
| Crossreactivity | Human |
| Quantity | 4x96wells |
| Sensitivity | 20pg/ml |
| AssayType | Sandwich |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Anyunusedreconstitutedstandardshouldbediscardedorfrozenat-80℃. Standardcanbefrozenandthawedonetimeonlywithoutlossofimmunoreactivity. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Superoxidedismutase(SOD)isanantioxidantenzymeinvolvedinthedefensesystemagainstreactiveoxygenspecies(ROS).SODcatalyzesthedismutationreactionofsuperoxiderADIcalanion(O2-)tohydrogenperoxide,whichisthencatalyzedtoinnocuousO2andH2Obyglutathioneperoxidaseandcatalase.SeveralclassesofSODhavebeenidentified.Theseincludeintracellularcopper,zincSOD(Cu,Zn-SOD/SOD-1),mitochondrialmanganeseSOD(Mn-SOD/SOD-2)andextracellularCu,Zn-SOD(EC-SOD/SOD-3)(1).SOD-1isfoundinalleukaryoticspeciesasahomodimeric32-kDaenzymecontainingoneeachofCuandZnionpersubunit(2).Themanganesecontaining80-kDatetramericenzymeSOD2,islocatedinthemitochondrialmatrixincloseproximitytoaprimaryendogenoussourceofsuperoxide,themitochondrialrespiratorychain(3).SOD-3isaheparin-bindingmultimerofdisulfide-linkeddimers,primarilyexpressedinhumanlungs,vesselwallsandairways(4).SOD-4isacopperchaperoneforsuperoxidedismutase(CCS),whichspecificallydeliversCutocopper/zincsuperoxidedismutase.CCSmayactivatecopper/zincsuperoxidedismutasethroughdirectinsertionoftheCucofactor.
