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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
| ProductDetails | |
|---|---|
| Synonyms | Proepithelin;PEPI;PCCell-derivedGrowthFactor |
| ProductType | Kit |
| Properties | |
| ApplicationSet | QuantitativeELISA |
| Specificity | Detectsratprogranulin.Doesnotcross-reactwithhumanprogranulin. |
| Crossreactivity | Rat |
| Quantity | 1x96wells 2x96wells(TwinPlex) |
| Sensitivity | 40pg/ml |
| Range | 0.063to4ng/ml |
| SampleType | CellCultureSupernatant Serum |
| AssayType | Sandwich |
| DetectionType | Colorimetric |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Afterstandardreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. Plateandreagentsshouldreachroomtemperaturebeforeuse. |
| Use/StABIlity | 12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Progranulin(PGRN)isawidelyexpressedpluripotentgrowthfactorwhichplaysaroleinprocessessuchasdevelopment,woundrepairandinflammationbyactivatingsignalingcascadesthatcontrolcellcycleprogressionandcellmotility.Itsfunctioninthecentralnervoussystemisofinterest,asmutationsinthePGRNgenewerefoundincasesoffrontotemporaldegeneration(FTLD).Inaddition,PGRNhasalsobeenlinkedtotumOrigenesis.Newcutting-edgepublicationshaveshownthatprogranulinmightbeabioMarkernotonlyforFTLD,butalsoforothertypesofAlzheimer‘sdisease(AD).ThisnewdataevensupposesthepotentialofprogranulintobeabiomarkerforMCI(MildCognitiveImpairment),whichwouldbeahallmarkinADresearch.Additionally,PGRNisdescribedasanewligandofTNFreceptorsandapotentialtherapeuticagainstinflammatorydiseaselikearthritis.
