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Adipogen/Flamma® 496 Maleimide/BCT-CWM1001-M001/1 mg

价格
¥2380.00
货号:BCT-CWM1001-M001
浏览量:75
品牌:Adipogen
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商品描述
More Information
Product Details
Product Type Chemical
Properties
Formula C27H18F2N2O8
MW 536.44
Source/Host Chemicals Synthetic.
Purity Chemicals >95% (TLC)
Appearance Yellow solid.
Solubility Soluble in DMSO or DMF.
Declaration Manufactured by BioActs.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping DRY ICE
Short Term Storage -20°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Flamma®496 is a fluorescent dye induced from Fluorescein structure and has a maximum value of Ex/Em at 496nm/516nm. Even though it is optically similar to FAM, it has features that are excellent light stability and better brightness compared to FAM. Flamma®496 Maleimide high-specifically bonds Thiol group (-SH) containing Cysteine on protein or peptide. After conducting pre-treatment process that reduces disulfide bond in protein using reducing agent such as DTT, TCEP or 2-mercaptoethanol prior to reaction, it can conjugate Flamma®496 Maleimide and protein. Excitation / Emission (nm): 496 / 516 nm. Extinction coefficient: 70,000 cm-1M-1. CF280: 0.12.

Adipogen科学研究的可重复性已成为一个主要问题,导致学术界和药物研究界对科学结果缺乏信任。正在进行的关于结果可重复性的对话包括未经正确验证的研究试剂(例如抗体)的作用。抗体是生命科学中的宝贵工具,已成为基础研究的重要工具。它们对独特的蛋白质靶标的高特异性和选择性使其成为必不可少的研究试剂。然而,尽管抗体被设计为识别靶蛋白,但它们可能无法在所有应用中都能够识别(例如那些改变靶蛋白结构的抗体)。在过去的几年中,为仅研究用(RUO)领域贡献商业抗体的抗体供应商的数量一直在稳定增长,其中用于确认敏感性,特异性,反应性和批次间一致性的验证数据不一致。 因此,由国际科学家委员会以及来自学术和行业实验室的领导人,期刊编辑和包括Adipogen Life Sciences在内的商业抗体供应商的领导者提出的许多倡议,提出了抗体验证的广泛指导方针以及详细的取决于环境的措施随后应由抗体供应商提供