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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
| ProductDetails | |
|---|---|
| Synonyms | FatMassandObesity-associatedProtein;FATSO |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | FT62-6 |
| Isotype | MouseIgG1κ |
| Immunogen/Antigen | RecombinanthumanFTO. |
| Application | ELISA:(directandindirect:1:2’000-1:5’000) Immunohistochemistry:(paraffinsections(1:100-1:500)) Immunoprecipitation:(5μg/mlpersampleinafinalreactionvolumeof500-1000μl). WesternBlot:(1:2’000-1:5’000usingECL.SuggestedblockinganddilutionbufferisPBSTcontaining0.05%Tween20and5%skimmilk.Suggestedincubationtimeis1houratroomtemperature). Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| Crossreactivity | Mouse |
| Specificity | RecognizesmouseFTO.Weaklycross-reactswithhumanFTO.Doesnotcross-reactwithratFTO. |
| PurityDetail | ProteinG-affinitypurified. |
| Concentration | 1mg/ml |
| Formulation | Liquid.0.2μm-filteredsolutioninPBS,pH7.4.Containsnopreservatives. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
FTO(Fatmass-andobesity-associatedgene)istheresponsIBLegeneformouse‘fusedtoes’mutation.AnassociationbetweenFTOgenotypeandtype2diabeteshasbeenconfirmed.ThepresenceoftheFTOrs9939609A-allelewasfoundtobepositivelycorrelatedwithothersymptomsofthemetabolicsyndrome,includinghigherfastinginsulin,glucose,triglycerides,andlowerHDL-cholesterol.
