Camptothecin sodium is sodium salt of an alkaloid compound camptothecin, which is used for cancer research. Camptothecin is produced from endosymbiotic Ascomycota (Phycomycete) fungi present in the tree Camptotheca acuminata or the plant Mappia foetida.

Camptothecin sodium is a topoisomerase I inhibitor in DNA synthesis. It has been shown to bind and stabilize a topoisomerase I-DNA complex in vitro, preventing the enzyme from reannealing DNA strands. This inhibition specifically effects the S-phase of cell development and ultimately results in apoptosis due to damaged DNA.

Product SpecificationsCamptothecinsodiumCamptothecin sodium saltSodiumcamptothecin

Formula: C₂₀H₁₇N₂NaO₅

MW: 388.35 g/mol

Storage/Handling: Store desiccated at room temperature.

PubChem Chemical ID: 23705698

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