Overview:
ProductName | ZM336372 |
Description | c-Rafkinaseinhibitor |
Purity | >95%(HPLC) |
CASNo. | 208260-29-1 |
MolecularFormula | C23H23N3O3 |
MolecularWeight | 389.4 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleinDMSO(200mg/ml) |
Source | Synthetic |
Appearance | Whitetooff-whitesolid |
SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O |
InChI | InChI=1S/C23H23N3O3/c1-15-7-10-18(24-23(29)17-5-4-6-19(13-17)26(2)3)14-21(15)25-22(28)16-8-11-20(27)12-9-16/h4-14,27H,1-3H3,(H,24,29)(H,25,28) |
InChIKey | PYEFPDQFAZNXLI-UHFFFAOYSA-N |
SafetyPhrases | Classification:Acutetoxicity,Oral(Category5)SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H303Maybeharmfulifswallowed. |
CiteThisProduct | ZM336372(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-488) |
BIOLOGicalDescription
AlternativeNames | N-[5-(3-Dimethylaminobenzamido)-2-methylphenyl]-4-hydroxybenzamide |
ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
PubChemID | 5730 |
ScientificBackground | ZM336372isapotent,specificandreversIBLeinhibitoroftheproteinkinasec-Raf.IthasalsobeenshowntoinhibitSAPK2/p38.ZM336372iscellpermeable. |
References | 1.Hall-JacksonC.A.,etal.(1999)Chem.Biol.6(8):559–568. |
ProductImages
ChemicalstructureofZM336372(SIH-488),ac-Rafkinaseinhibitor.CAS#:208260-29-1.MolecularFormula:C23H23N3O3.MolecularWeight:389.4g/mol.
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