品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Overview:
| ProductName | SC79 |
| Description | Aktkinaseactivator |
| Purity | >97%(NMR) |
| CASNo. | 305834-79-1 |
| MolecularFormula | C17H17ClN2O5 |
| MolecularWeight | 364.8 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Activator |
| Solubility | Solubleto100mMinDMSO |
| Source | Synthetic |
| Appearance | Whitesolid |
| SMILES | CCOC(=O)C1=C(OC2=C(C1C(C#N)C(=O)OCC)C=C(C=C2)Cl)N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | SC79(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-512) |
BIOLOGicalDescription
| AlternativeNames | SC-79,SC79,2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-aceticacidethylester |
| ResearchAreas | CellSignaling |
| ScientificBackground | SC79isanactivatorofAkt(proteinkinaseB).Specifically,ithasbeenshowntobindtheplecktrinhomology(PH)domainofAkt.ThismimicsthebindingofPhosphatidylinositol(3,4,5)-trisphosphates,whichinducesaconformationalchangeinAkt,thatenhancesphosphorylationandactivation. |
| References | 1.JoH.,etal.(2012)Pro.Nat.Acad.Sci.USA.109(26):10581–10586. |
ProductImages

ChemicalstructureofSC79(SIH-512),aAktkinaseactivator.CAS#:305834-79-1.MolecularFormula:C17H17ClN2O5.MolecularWeight:364.8g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.


