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商品描述
Overview:
| ProductName | PK-11195 |
| Description | Benzodiazepinereceptorligand |
| Purity | >98% |
| CASNo. | 85532-75-8 |
| MolecularFormula | C21H21CIN2O |
| MolecularWeight | 352.86 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inducer |
| Solubility | Solubleto75mMinethanolandto100mMinDMSO |
| Source | Synthetic |
| Appearance | WhiteCrystals |
| SMILES | CCC(C)N(C)C(=O)C1=CC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl |
| InChI | InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3 |
| InChIKey | RAVIZVQZGXBOQO-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R20/21/22-Harmfulbyinhalation,incontactwithskinandifswallowedR68-PossIBLeriskofirreversibleeffects |
| CiteThisProduct | PK-11195(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-224) |
BIOLOGicalDescription
| AlternativeNames | N-sec-Butyl-1-(2-chlorophenyl)-N-methyl-3-isoquinolinecarboxamide |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 1345 |
| ScientificBackground | PK-11195isanisoquinolinecarboxamidewhichbindsselectivelytotheperipheralbenzodiazepinereceptor(PBR).IthasahighaffinityforthePBRinallspecies(1).IthasalsobeensuccessfullyusedinPETscanstovisualizebraininflammationinpatientswithneuronaldamage(2). |
| References | 1. PikeV.W.,etal.(1993)NuclMed&Bio.20(4):503-525. 2.BuckJ.R.,etal.(2011)JNuclMed.52(1):107-114. |
ProductImages

ChemicalstructureofPK-11195(SIH-224),aMitochondrialbenzodiazepinereceptorligand.CAS#:85532-75-8.MolecularFormula:C21H21CIN2O.MolecularWeight:352.86g/mol.
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