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StressMarq/Anti-LKB1 Antibody/SPC-1156D-A655/100-µl

价格
¥6840.00
货号:SPC-1156D-A655
浏览量:127
品牌:StressMarq
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商品描述

Overview:

Product Name LKB1 Antibody
Description

Rabbit Anti-Human LKB1 Polyclonal

Species Reactivity Human, Mouse
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen Synthetic peptide corresponding to the N-terminus of human LKB1 (AA1-15)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 49 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1156, RRID: AB_2711207
Certificate of Analysis A 1:250 dilution of SPC-1156 was sufficient for detection of LKB1 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names hLKB1 antibody, Liver kinase B1 antibody, LKB1 antibody, PJS antibody, Polarization related protein LKB1 antibody, Renal carcinoma antigen NY-REN-19 antibody, Serine/Threonine Kinase 11 antibody, Serine/threonine protein kinase STK11 antibody, Stk11 antibody, STK11_HUMAN antibody
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_000446
Gene ID 6794
Swiss Prot Q15831
Scientific Background LKB1 is a protein-serine/threonine kinase. Phosphorylates and activates AMP-activated kinase (AMPK), AMPK involved in stress responses, lipid and glucose metabolism. Its mutation pattern in human tumours is very characteristic of a tumour suppressor protein.

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 ATTO 655
Overview:

  • High fluorescence yield
  • High thermal and photostability
  • Excellent ozone resistance
  • Quenched by electron donors
  • Very hydrophilic
  • Good solubility in polar solvents
  • Zwitterionic dye
  • Molar Mass: 634 g/mol

ATTO 655 Datasheet

ATTO 655 Fluorophore Absorption and Emission SpectrumOptical Properties:

λex = 663 nm

λem = 684 nm

εmax = 1.25×105

Φf = 0.30

τfl = 1.8 ns

Brightness = 37.5

Laser = 633 – 647 nm

Filter set = Cy®5

 

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