Overview:
ProductName | D-LAP5 |
Description | NMDAreceptorantagoNIST |
Purity | >99.0 |
CASNo. | 76326-31-3 |
MolecularFormula | C5H12NO5P |
MolecularWeight | 197.13 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Antagonist |
Solubility | Solubleto10mMinwaterandto100mMin1eq.NaOH |
Source | Synthetic |
Appearance | Whitesolid |
SMILES | C([P](O)(O)=O)CCC(C(O)=O)N |
InChI | InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11) |
InChIKey | VOROEQBFPPIACJ-UHFFFAOYSA-N |
SafetyPhrases | Classification:D2BToxicMaterialCausingOtherToxicEffects,Moderateskinirritant,Moderaterespiratoryirritant,ModerateeyeirritantSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P271Useonlyoutdoorsorinawell-ventilatedarea.P280Wearprotectivegloves/eyeprotection/faceprotection.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing. |
CiteThisProduct | D-LAP5(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-413) |
BIOLOGicalDescription
AlternativeNames | DL-amino-5-phosphonopentaoicacid |
ResearchAreas | GlutamateReceptors,IonChannels,Neuroscience,NeurotransmitterReceptors,NMDAReceptors |
PubChemID | 1216 |
ScientificBackground | DLAP5isaracemicmixture.ItisusedwidelyasapotentandselectiveNMDAreceptorantagonist.ItrepresentstheactiveenantiomerformofAP5(2-amino-5-phosphonopentanoicacid). |
References | 1.DaviesJ.,&WatkinsJ.(1982)BrainRes.378-86. 2.SchulteM.,RoonR.,ChalmersD.,SunterD.,&KoernerJ.(1994)BrainRes.203-7. |
ProductImages
ChemicalstructureofD-LAP5(SIH-413),aGlutamate-NMDAreceptorantagonist.CAS#:76326-31-3.MolecularFormula:C5H12NO5P.MolecularWeight:197.13g/mol.
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