Overview:
ProductName | 6-Formylindolo(3,2-b)carbazole |
Description | Ahreceptorligand |
Purity | >95% |
CASNo. | 172922-91-7 |
MolecularFormula | C19H12N2O |
MolecularWeight | 284.3 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Ligand |
Solubility | SolubleinDMSO(10mg/ml) |
Source | Synthetic |
Appearance | Yellowsolid |
SMILES | C1=CC=C2C(=C1)C3=CC4=NC5=CC=CC=C5C4=C(C3=N2)C=O |
InChI | InChI=1S/C19H10N2O/c22-10-14-18-12-6-2-4-8-16(12)20-17(18)9-13-11-5-1-3-7-15(11)21-19(13)14/h1-10H |
InChIKey | OTWFDHQTFRXSAK-UHFFFAOYSA-N |
SafetyPhrases | Classification:Caution.Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
CiteThisProduct | 6-Formylindolo(3,2-b)carbazole(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-383) |
BIOLOGicalDescription
AlternativeNames | Indolo[3,2-b]carbazole-6-carbaldehyde,FICZ |
ResearchAreas | CellSignaling |
PubChemID | 22245026 |
ScientificBackground | Atryptophan-derived,highaffinityarylhydrocarbonreceptorligand(Kd=7x10-11M).ProposedtobeanendogenousAhRligand.InducesrapidandtransientexpressionofcytochromeP450-1A1(CYP1A1)inhumancellsat100pM. |
References | 1.WeiY.D.,etal.(1998)Chem.Biol.Interact.110(1-2):39-55. 2.RannugU.,etal.(1995)Chem.Biol.Drug.Des.2(12):841-855. 3.RannugA.,etal.(1987)J.Biol.Chem.262(32):15422-7. |
ProductImages
Chemicalstructureof6-Formylindolo(3,2-b)carbazole(SIH-383),aAhreceptorligand.CAS#:172922-91-7.MolecularFormula:C19H12N2O.MolecularWeight:284.3g/mol.
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