FactorVLightChainMonoclonalAntibody

ORDERINGINFORMATION

CatalogNo.:19701(cloneB38)Format:250ugProteinG-purifiedantibodyinPBS,pH7.4

BACKGROUND

CoagulationcofactorV(FactorV)isahighmolecularweightglycoproteinthatperformsseveralcriticalfunctionsinregulatinghemostasis.Initsthrombin-activatedform(FVa)itinteractswithFactorXaandCa+2toformtheprothrombinasecomplex.ThiscomplexcatalyzestheformationofthrombinfromprothrombinatratessubstantiallyhigherthanFactorXaalone.

SPECIFICATIONSUMMARY

Antigen:PurifiedhumanFactorV.HostSpecies:MouseAntibodyClass:IgG1Specificity:ThisantibodyrecognizestheF1F2polypeptideofhumanFactorValightchain.

APPLICATIONS

Westernblotting:abandofapprox.74kDaisdetected.

ELISA

DILUTIONINSTRUCTIONS

DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

PRODUCTREFERENCES

GewirtzAMetal.1986Blood67:1639-1648.

AnnamalaiAEetal.1987Blood70:139-156.

Forinvitroinvestigationaluseonly.Notintendedfortherapeuticordiagnosticapplications.

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