CatalogNo. 15801 | CloneNo. GC12-316.4 | MAbSubtype IgG3* | Size 100ug,500ug | LibraryPackNo. 158101 | 100ug/clone All4clones |
15802 | GC12-323.6 | IgG1** | 100ug,500ug | ||
15803 | GC12-351.2 | IgG1** | 100ug,500ug | ||
15804 | GC12-351.4 | IgG1** | 100ug,500ug |
CatalogNo. 15801 | CloneNo. GC12-316.4 | MAbSubtype IgG3* | Size 100ug,500ug | LibraryPackNo. 158101 | 100ug/clone All4clones |
15802 | GC12-323.6 | IgG1** | 100ug,500ug | ||
15803 | GC12-351.2 | IgG1** | 100ug,500ug | ||
15804 | GC12-351.4 | IgG1** | 100ug,500ug |
ORDERINGINFORMATION
Format:*PEG-purifiedantibodyinPBS,pH7.4
**ProteinG-purifiedantibodyinPBS,pH7.4
BACKGROUND
Neisseriagonorrhoeaeisagram-negativecoccusandisthecauseofthesexuallytransmitteddiseasegonorrheawithhumansasitsonlynaturalhost.Althoughitdoesnotproduceanyexotoxins,Neisseriagonorrhoeaehasawiderangeofvirulencedeterminants.Thefirststagesofinfection,whichincludeadherenceandinvasion,aremediatedbysurfacecomponents;N.gonorrhoeaefirstattachestoepithelialcellsbymeansofitsfimbriae.Afterinitialattachment,thebacteriaenterasecondstageofbindingmediatedbytheoutermembraneproteinP.II(alsoknownasOpa)whichisneededfortightbindingandinvasionofepithelialcells.P.IIfromonebacteriumwillbindtolipooligosaccharideofanadjacentbacterium,whichallowsfortheconstructionofasmallcolonythatmayfunctionsimilarlytoabiofilm.NeisseriagonorrhoeaealsoproducesanIgA1proteasethatmaytakepartinthecolonizationstage.
SPECIFICATIONSUMMARY
Antigen:PoolofUV-inactivatedNeisseriagonorrhoeaecells:NeisseriaReferencelaboratorystrainsG-7,R-11,and7122(W-I),5766and8038(W-II),and8660(W-III).
HostSpecies:Mouse
Specificity:TheseantibodiesrecognizeN.gonorrhoeae.Theydonotcross-reactwithN.meningitides,N.cinerea,N.lactamica,N.sicca,B.catarrhalis,E.coli,ProteusmirABIlis,Gardnerellavaginalis,GroupBStrep.orChlamydiatrachomatis.
APPLICATIONS
TheseantibodieshavebeenqualifiedforuseinELISAtodetectN.gonorrhoeae.Endusersshoulddetermineoptimalconcentrationsfortheirapplications.
DILUTIONINSTRUCTIONS
DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.
STORAGEANDSTABILITY
Theseantibodiesarestableforatleastone(1)yearat-20oto-70oC.Storeproductinappropriatealiquotstoavoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notintendedforuseintherapeuticordiagnosticprocedures.
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