productdatasheet

DC-SIGN(ED)PolyclonalAntibody

ORDERINGINFORMATION

CatalogNo.:18711

Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.

SPECIFICATIONSUMMARY

Antigen:Peptidecorrespondingtoaa277-293ofhumanDC-SIGN.

HostSpecies:Rabbit

StABIlizers:None

Preservatives:0.02%sodiumazide

SPECIFICITY

ThisantibodyrecognizeshumanDC-SIGN,adendriticcellreceptorthatcancaptureandtransportHIVfrommucosalareastoremotelymphnodeswhereHIVisthentransferredtoCD4+Tlymphocytes.MultiplestrainsofHIV-1,HIV-2,andSIVbindtodendriticcellsviaDC-SIGN.DC-SIGNisexpressedinmucosaltissues,placenta,smallintestine,andrectum.

APPLICATIONS

Immunoblotting:useat1-2ug/ml.Inimmunoblots,abandof44kDisdetected.

Positivecontrol:Humanplacentatissuelysate.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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