ORDERINGINFORMATION
CatalogNo. | CloneNo. | MAbSubtype | Size |
12005 | RF2-17.109.2 | IgG2b | 100ug,500ug |
Format:ProteinGpurifiedantibodyinPBS,pH7.4
BACKGROUND
AntibodiesdirectedagainsttheFcfragmentofimmunoglobulinG(IgG)arecalledrheumatoidfactors(RFs).TheyareheterogenousandareusuallyIgMantibodies.RFsareusedasaMarkerinindividualswithsUSPectedrheumatoidarthritis(RA)orotherautoimmuneconditions.ThenormalreferencerangeforRFislessthan15IU/mL
SPECIFICATIONSUMMARY
Antigen:PurifiedproteinsfrompatientswithIgMcryoglobulins.
HostSpecies:Mouse
Specificity:Thisantibodyreactswith30%ofIgM-RFfromunrelatedindividuals.ItdoesnotrecognizeIgM,IgA,orIgGproteinslackingRFnorwithF(ab’)2fragments.
APPLICATIONS
ThisantibodyhasbeenqualifiedforuseinELISAtodetecthumanrheumatoidfactor.
DILUTIONINSTRUCTIONS
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
STORAGEANDSTABILITY
Thisantibodyisstableforatleastone(1)yearat-20oCto-70oC.Storeproductinappropriatealiquotstoavoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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