productdatasheet
CatalogNo.:40104
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.
Antigen:Peptidecorrespondingtoaa97-111ofhumanIL-21Rprecursor.
HostSpecies:Rabbit
StABIlizers:None
Preservatives:0.02%sodiumazide
ThisantibodyrecognizeshumanIL-21R,thereceptorforIL-21.IL-21Rcomplexeswiththecommoncytokinereceptorγchain,γc,andmediatesIL-21signaling.IL-21anditsreceptoractivatetheJAK-STATsignalingpathway.IL-21Risexpressedinspleenandthymusaswellasonnaturalkiller(NK),TandBcellsandplaysaroleintheproliferationandmaturationofthesecellpopulations.
APPLICATIONSImmunoblotting:useat0.5-1ug/ml.Inimmunoblots,abandof60kDisdetected.
Positivecontrol:Rajicelllysate.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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