productdatasheet

APRIL(ED2)PolyclonalAntibody

ORDERINGINFORMATION

CatalogNo.:41001

Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.

SPECIFICATIONSUMMARY

Antigen:Peptidecorrespondingtoaa196-210ofhumanAPRIL.

HostSpecies:Rabbit

StABIlizers:None

Preservatives:0.02%sodiumazide

SPECIFICITY

ThisantibodyrecognizeshumanAPRIL(AProliferation-InducingLigand),anovelmemberoftheTNFfamily.TworeceptorsforAPRIL,TACIandBCMAwererecentlyidentified.APRILstimulatesBandTcellproliferation,triggershumoralimmuneresponses,activatesNF-κB,andinducescelldeath.APRILisassociatedwithautoimmunediseasesandcancer.

APPLICATIONS

Immunoblotting:useat2-4ug/ml.Inimmunoblots,abandof42kDisdetected.

Positivecontrol:HL60orJurkatcelllysates.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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SanDiego,CA92127

TollFree800.929.2114

Phone858.675.2405

Fax858.592.1509

info@qedbio.com

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