ValproicAcidMonoclonalAntibodies

ORDERINGINFORMATION

CatalogNo. 16801	CloneNo. VP10-115.2	MAbSubtype IgG1	Size 100ug,500ug	LibraryPackNo. 168101	100ug/clone All5clones
16802	VP10-201.7	IgG1	100ug,500ug
16803	VP10-234.5	IgG1	100ug,500ug
16804	VP13-607.1	IgG1	100ug,500ug
16805	VP13-615.3	IgG1	100ug,500ug

Format:ProteinG-purifiedantibodyinPBS,pH7.4.

BACKGROUND

Valproicacidisprimarilyusedtotreatepilepsyandbipolardisorderandtopreventmigraineheadaches.Ithasrecentlybeenshowntoprotectagainstaseizure-inducedreductioninphosphatidylinositol(3,4,5)-trisphosphate(PIP3)asapotentialtherapeuticmechanism.Inaddition,itsanticonvulsanteffecthasbeenattributedtotheblockadeofvoltage-dependentsodiumchannelsandincreasedbrainlevelsofgamma-aminobutyricacid(GABA).

Valproicacidwasfirstmadein1881andcameintomedicalusein1962.ItisontheWorldHealthOrganization'sListofEssentialMedicines.

SPECIFICATIONSUMMARY

Antigen:ValproicacidconjugatedtoKLH.

HostSpecies:Mouse

Specificity:Theseantibodiesrecognizevalproicacid.

APPLICATIONS

TheseantibodieshavebeenqualifiedforuseinELISAtodetectvalproicacid.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Theseantibodiesarestableforatleastone(1)yearat-20oCto-70oC.Storeproductinappropriatealiquotstoavoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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