productdatasheet

PID/MTA2PolyclonalAntibody

ORDERINGINFORMATION

CatalogNo.:56227

Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.

SPECIFICATIONSUMMARY

Antigen:Peptidecorrespondingtoaa652-668ofhumanPID/MTA2.Thissequencediffersfromthatofmousebyoneaminoacid.

HostSpecies:Rabbit

StABIlizers:None

Preservatives:0.02%sodiumazide

SPECIFICITY

Thisantibodyrecognizeshuman,mouse,andratPID/MTA2,asubunitofthenucleosomeremodelinganddeacetylating(NRD/NuRD)complex.PID/MTA2modulatestheenzymaticactivityofthehistonedeacetylasecomplex,anditsexpressionreducesthelevelsofacetylatedp53.Deacetylationofp53byPID/MTA2repressesp53-dependenttranscriptionalactivationandmodulatesp53-mediatedcellgrowtharrestandapoptosis.PID/MTA2isexpressedinavarietyoftissues.Thisantibodydoesnotcross-reactwithMTA1.

APPLICATIONS

Immunoblotting:useat0.5-1ug/ml.Inimmunoblots,abandof75kDisdetected.

Positivecontrol:HeLacelllysate.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

QEDBioscience,Inc.10919TechnologyPlace,SuiteC

SanDiego,CA92127

TollFree800.929.2114

Phone858.675.2405

Fax858.592.1509

info@qedbio.com

Visitourwebsiteforadditionalproductinformationandtoorderonline.

qedbio.com

QED Bioscience为您的所有生物学研究需求提供大量定制服务，例如定制抗体生产，细胞培养服务，细胞系开发和细胞库。我们的定制抗体服务包括多克隆和单克隆抗体生产，体外抗体生产和抗体纯化。