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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Cataloguenumber
PRO-2195
Synonyms
Albumin,CellGrowthInhibitingProtein42,Growth-InhibitingProtein20,Albumin(32AA),Albumin(AA34),SerumAlbumin,PRO0883,PRO0903,PRO1341,ANALBA,FDAH,HAS,ALB.
Introduction
AlbuminissynthesizedintheliveraspreproalbuminwhichhasanN-terminalpeptidethatisremovedbeforethenascentproteinisreleasedfromtheroughendoplasmicreticulum.Theproduct,proalbumin,isinturncleavedintheGolgivesiclestoproducethesecretedalbumin.Albuminisasoluble,monomericproteinwhichcomprisesaboutone-halfofthebloodserumprotein.Albuminfunctionsprimarilyasacarrierproteinforsteroids,fattyacids,andthyroidhormonesandplaysaroleinstABIlizingextracellularfluidvolume.Mutationsinthisgeneonchromosome4resultinvariousanomalousproteins.Albuminisaglobularunglycosylatedserumproteinofmolecularweight65,000.Thehumanalbumingeneis16,961nucleotideslongfromtheputative"cap"sitetothefirstpoly(A)additionsite.Itissplitinto15exonswhicharesymmetricallyplacedwithinthe3domainsthatarethoughttohavearisenbytriplicationofasingleprimordialdomain.
HSAiswidelyusedtostabilizebloodvolumegenerallyfromdonorsbutthefearofcontaminationsuchasHIV&Hepatitishasenticedgreatinterestintherecombinantformwhichisidenticaltothenaturalblood.
HSAiswidelyusedtostabilizebloodvolumegenerallyfromdonorsbutthefearofcontaminationsuchasHIV&Hepatitishasenticedgreatinterestintherecombinantformwhichisidenticaltothenaturalblood.
Description
HSAproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechain(19-609a.a.)andfusedtoa6aaHisTagatC-terminuscontainingatotalof597aminoacidsandhavingamolecularmassof68kDa.
HSAshowsmultiplebandsbetween50-70kDaonSDS-PAGE,reducingconditionsandpurifiedbyproprietarychromatographictechniques.
HSAshowsmultiplebandsbetween50-70kDaonSDS-PAGE,reducingconditionsandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Sterilefilteredcolorlesssolution.
Formulation
HSAproteinsolution(0.5mg/ml)containsPhosphatebufferedsaline(pH7.4)and10%glycerol.
Stability
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
RGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLHHHHHH
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.