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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
Catalogue number
PRO-448
Introduction
Plasma fibronectin level is elevated in severe coronary artery disease. Increased plasma fibronectin levels are related with venous thromboembolism (VTE) particularly in males, and extend the probable association between biomarkers and risk factors for arterial atherothrombosis and VTE. Fibronectin plays a role in several cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion. Fibronectin consists in two main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the extracellular matrix and 2) as a soluble disulphide linked dimer found in the plasma. The plasma form is produced by hepatocytes, and the ECM form is synthesized by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells. Fibronectin also takes part as a general cell adhesion molecule by anchoring cells to collagen or proteoglycan substrates. Fibronectin organizes cellular interaction with the ECM by binding to different components of the extracellular matrix and to membrane-bound Fibronectin receptors on cell surfaces.
Description
Human Fibronectin produced purified from Human Plasma having a Molecular Weight of 450kDa.
Source
Human Plasma.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
The Fibronectin was lyophilized from a concentrated 1mg/ml solution containing 0.05M Tris Cl pH-7.5 and 0.1M NaCl.
Solubility
Purified fibronectin has a tendency to form insoluble aggregates upon reconstitution. We suggest reconstituting the 1mg Fibronectin with a chaotropic agent such as urea at room temperature at a concentration of 0.2mg/ml using sterile water. Let stand 1-2 hours. The recommended concentration is 4M-5M urea. When using the protein as an attachment factor, wash the urea off after attaching the fibronectin to the growth surface (plate or dish).
Stability
Store the lyophilized fibronectin at 4°C. Upon reconstitution fibronectin should be stored at 4°C for 2 weeks and for future use below -18°C.Please prevent freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Safety Data Sheet
SDS
Usage
ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec是全球著名细胞因子蛋白及相关抗体生产和研发品牌，专注于蛋白生产研发，独有细菌和哺乳动物表达和蛋白折叠技术。目前可提供细胞因子、生长因子、激素、信号蛋白、病毒抗原等近800种重组蛋白和100多种抗体。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
产品列表：
No.
品牌
货号
名称
规格
1
ProSpec
PRO-1574
BCL2 Human
5µg
2
ProSpec
CYT-1075
IFNA7 Human, Sf9
2µg
3
ProSpec
CHM-328
Rantes Human
5µg
4
ProSpec
CHM-330
IP 10 Human
5µg
5
ProSpec
CYT-575
MIF Human
5µg
6
ProSpec
CYT-538
GH Antagonist Chicken
20µg
7
ProSpec
CYT-1043
TNFRSF10A Human
2µg
8
ProSpec
PRO-2390
CD2 Human, Sf9
2µg
9
ProSpec
PRO-2237
CD47 Human
2µg
10
ProSpec
CYT-581
Beta NGF Mouse
5µg
11
ProSpec
CYT-973
NRP1 Rat
1µg
12
ProSpec
HOR-253
FSH Human
2µg
13
ProSpec
HOR-275
Thymosin beta 4
1mg
14
ProSpec
DEN-005
Dengue Envelope-1 22kDa
100µg
15
ProSpec
HEV-235
HEV Mosaic
100µg
