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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Catalogue number
PRO-2225
Synonyms
DHLAG, HLADG, Ia-GAMMA, li, HLA-DR antigens-associatedinvariant chain, p33, Ia antigen-associated invariant chain, HLA class IIhistocompatibility antigen gamma chain, CD74, Gamma Chain Of Class II Antigens,MHC HLA-DR Gamma Chain.
Introduction
CD74 (HLA class II histocompatibility antigen gamma chain isoform b), is a transmembrane protein (on antigen presenting cells) which is the invariant chain that chaperones MHC class IIdimers from the endoplasmic reticulum to the cell surface. CD74 is expressed by cells of both T lymphocyte and Blymphocyte lineages. CD74 upregulated in several cancers and is also expressed by non immune cells during inflammation. Diseases related with CD74 include thymic epithelial neoplasm and gastroduodenitis. Among its related super-pathways are Immune System and Immune response Antigen presentation by MHC class II. In addition CD74 functions as cell surface receptor for the cytokine MIF.
Description
CD74 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 166 amino acids (73-232a.a.) andhaving a molecular mass of 19.05kDa (Molecular size on SDS-PAGE will appear atapproximately 18-28kDa). CD74 is expressed with a 6 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
CD74 protein solution (0.5mg/ml) contains phosphatebuffered saline (pH7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
QQQGRLDKLT VTSQNLQLEN LRMKLPKPPK PVSKMRMATP LLMQALPMGALPQGPMQNAT KYGNMTEDHV MHLLQNADPL KVYPPLKGSF PENLRHLKNT METIDWKVFE SWMHHWLLFEMSRHSLEQKP TDAPPKESLE LEDPSSGLGV TKQDLGPVPM HHHHHH.
Safety Data Sheet
SDS
Usage
Prospec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec是全球著名细胞因子蛋白及相关抗体生产和研发品牌，专注于蛋白生产研发，独有细菌和哺乳动物表达和蛋白折叠技术。目前可提供细胞因子、生长因子、激素、信号蛋白、病毒抗原等近800种重组蛋白和100多种抗体。
ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research.
Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more.....
产品列表：
No.
品牌
货号
名称
规格
1
ProSpec
PRO-1574
BCL2 Human
5µg
2
ProSpec
CYT-1075
IFNA7 Human, Sf9
2µg
3
ProSpec
CHM-328
Rantes Human
5µg
4
ProSpec
CHM-330
IP 10 Human
5µg
5
ProSpec
CYT-575
MIF Human
5µg
6
ProSpec
CYT-538
GH Antagonist Chicken
20µg
7
ProSpec
CYT-1043
TNFRSF10A Human
2µg
8
ProSpec
PRO-2390
CD2 Human, Sf9
2µg
9
ProSpec
PRO-2237
CD47 Human
2µg
10
ProSpec
CYT-581
Beta NGF Mouse
5µg
11
ProSpec
CYT-973
NRP1 Rat
1µg
12
ProSpec
HOR-253
FSH Human
2µg
13
ProSpec
HOR-275
Thymosin beta 4
1mg
14
ProSpec
DEN-005
Dengue Envelope-1 22kDa
100µg
15
ProSpec
HEV-235
HEV Mosaic
100µg
