Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllMyelinBasicProtein(MBP)isamajorcomponentofthemyelinsheathofoligodendrocytesandSchwanncellsinthenervoussystem,although,MBP-relatedtranscriptsarealsopresentinthebonemarrowandtheimmunesystem.ThesemRNAsemergefromthelongMBPgenewhichholdsthreeadditionalexonslocatedupstreamoftheclassicMBPexons.TheGollimRNAscontainthreeexonsuniquetoGolli-MBP,splicedin-frametooneormoreMBPexons.ThesecondfamilyoftranscriptscontainsonlyMBPexonsandproducesthewellcharacterizedmyelinbasicproteins.MBPtranscriptionunitisanessentialpartoftheGollitranscriptionunitandthearrangementisimportantforthefunctionand/orregulationofthesegenes.Includethewrite-upofyourproducthere.
MBPHumanRecombinantproducedinE.coliisasingle,non-glycosylatedpolypeptidechaincontaining220aminoacids(1-197)andhavingamolecularmassof23.9kDa.
MBPisfusedtoa23aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.
