Type:GoatIgG
Applications:IHC;WB
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:M
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:ProteinGPurified-liquid
Immunogen:RecombinantmouseADAM10ectodomain
MembersoftheADAMorMDC(Metalloprotease,Disintegrin,Cysteine-rich)familycontainpro,metalloprotease-like,disintegrin-like,cysteine-rich,transmembraneandcytoplasmicdomains.Theyplayafundamentalroleindiverseprocessessuchasasthma,development,angiogenesisandcancerthroughtheiractivitiesincelladhesion/fusion,membraneproteinshedding,andsignaltransduction.Over30membershavebeenidentifiedandabouthalfofthemareactivemetalloproteasessuchasADAM8,9,10,12and17/TACE.
Image:DetectionofADAM10incryostatsectionsofmousebrainusinggoatanti-mouseADAM10antibody.Tissueswerestainedusinganti-goatHRP-DAB(browncolor)Cellandcounterstainedwithhematoxylin(bluecolor).