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Type:GoatIgG
Applications:IHC;WB;E
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:NS0-derived,recombinanthumanTie2(rhTie2)extracellulardomain.
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Tie-1/Tie(tyrosinekinasewithIgandEGFhomologydomains1)andTie-2/Tekcompriseareceptortyrosinekinase(RTK)subfamilywithuniquestructuralcharacteristics:twoimmunoglobulin-likedomainsflankingthreeepidermalgrowthfactor(EGF)-likedomains,followedbythreefibronectintypeIII-likerepeatsintheextracellularregionandasplittyrosinekinasedomaininthecytoplasmicregion.ThesereceptorsareexpressedprimarilyonendothelialandhematopoieticProgenitorcellsandplaycriticalrolesinangiogenesis,vasculogenesisandhematopoiesis.
Image:Tie-2StaininginParaffin-embeddedtissuesectionsofhumanplacenta(cross-sectionthroughthebloodvessel)werestainedwithanti-goatHRP-AEC(red)andHaematoxylin(blue)counterstain.