Type:GoatIgG
Applications:IHC;WB
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:R
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:E.coli-derived,recombinantratinterleukin2(rrIL-2).

Interleukin2(IL-2)wasinitiallyidentifiedasaTcellgrowthfactorthatisproducedbyTcellsfollowingactivationbymitogensorantigens.Sincethen,ithasalsobeenshowntostimulatethegrowthanddifferentiationofBcells,naturalkiller(NK)cells,lymphocyteactivatedkiller(LAK)cells,monocytes/macrophagesandoligodendrocytes.Attheaminoacidsequencelevel,thereisapproximately60-90%similaritybetweenspecies.MaturehumanIL-2shares60%,72%,72%,78%,and86%similaritieswithmouse,equine,porcine,feline,andcanine,respectively.
Image: IL-2 stainingof ratspleentissuesectionfromDAratsufferingfromcollagen-inducedarthritis.CellswerestainedusingDABastheperoxidasesubstrate.


