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TNF-alphaisapotentpleiotrophiccytokine,producedbywhitebloodcells,endotheliumandseveralothernormalandtumorcellsinresponsetoawidevarietyofstimuli.TNF-alphaisinvolvedinthepathophysiologicalprocessesofseveralchronicandacutediseasesincludingtheinductionofapoptosisandupregulationofinflammation.
TherecombinantTNF-alphacomprisesa157aminoacidfragment(77-233)correspondingtothematuresolubleTNF-alphachainprotein.TNF-alphaisexpressedinE.coliwithanamino-terminalhexahistidinetag.
Form:liquid
Purity:95%SDS-PAGE
Storage:Storeat-20°C.