Tumornecrosisfactoralpha(TNF-α)isapotentcytokinewithamyriadofinnateimmuneanti-tumorproperties.TNF-αhasacriticalroleintheboneandcartilagedamageassociatedwithrheumatoidarthritis(RA).TNF-αmaybeinvolvedinthepathogenesisand/orprogressionofgestationaldiabetesmellitus(GDM).TNF-αisexpressedinmyocardiumduringcompensatedpressure-overloadhypertrophyandcontributestopostischemicmyocardialdysfunction.TheserumlevelsofTNF-αwerealsosignificantlyelevatedinactiveWG(Wegener’sgranulomatosis)inthelatestagesofHIV-associateddiseaseandinthespinalcordofarthriticpatients.
Species:human
SampleType: serum,plasma,cellculturesupernates
SampleSize:50uL
StandardCurveRange: 0-1ng/mL
Sensitivity: 0.01ng/mL
AssayLength: 5hours