Interleukin-10(IL-10)isaregulatorycytokine,anditsprincipalroleinvivoistolimitinflammatoryresponse.IL-10hasbeenshowntoinfluenceboththesusceptibilityandcourseofvariousdiseases.Monocytesfromindeterminate-diseasepatientsdisplaymodulatorycharacteristicsrelatedtohighIL-10expression;whereas,monocytesfromcardiac-diseasepatientsmaybecommittedtoinductionofinflammatoryresponsesrelatedtohighTNF-αexpression.Interleukin10(IL-10)isakeycytokineproducedbyamultitudeofimmuneeffectorcellsandpossessesdistinctregulatoryeffectsonimmunefunctioningintheskin.TheacceleratedalveolarbonelossobservedinIL-10(-/-)miceisalate-onsetconditionandthatlackofIL-10mayhaveaneffectonbonehomeostasis.
Species:human
SampleType: serum,plasma,cellculturesupernates,tissueextracts
SampleSize:50uL
StandardCurveRange: 0.125-4ng/mL
Sensitivity: 0.012ng/mL
AssayLength: <5hours
