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Methotrexateisintheclassofmedicationscalledantimetabolites.Thedrugisusedtotreatseverepsoriasis,rheumatoidarthritisandcertaintypesofcancer.Itworksbyslowingtheproliferationofcells.Specifically,itinhibitstheenzymedihydrofolatereductasethatisnecessaryforthesynthesisoffolicacid,whichisrequiredforthesynthesisofDNA,RNA,thymidylatesandproteins.
Immunogen:Methotrexate-BSA
HostAnimal:Sheep
Format:IgFraction
IgConcentration:7.74mg/ml(U.V.abs@280nm)
WorkingDilution:2.5μg/ml(EIA)
pH:7.2
Buffer:20mMPhosphate,150mMSodiumChloride
Preservative:0.09%SodiumAzide
Storage:-20°C