ProductHighlights:
TheBovineLDBeadChipmicroarraykitenablesaccurategenotypingtounderstandtheimpactofgeneticsonmilkproduction,reproduction,health,andmore.Deliveringsuperior,scalablecontentataneconomicalprice,itallowsyoutoextendgenomicselectiontotheentireherd.Thisarrayoffers:
- Arobustimputationtooltoestimategenomicbreedingvalueaccurately
- Highcallrates,withdemonstratedimputationefficiencyof>98%
- Expertlyselectedcontentthatcanbeenhancedwithupto80,000customMarkers
- Containsall200SNPsontheISAGpanelforbovineparentage(100coreSNPsand100additionalSNPs)
- TheABIlitytointerrogateupto24samplesinparallel
Cost-EffectiveGenotypingofHerdAnimals
TheBovineLDv2.0BeadChip,togetherwiththeInfiniumBovineSNP50,InfiniumBovineHD,andiSelectCustomBeadChips,createsabroadgenotypingportfoliothatbreederscanrelyontocharacterizegeneticvariationandaccuratelyestimategenomicbreedingvalue.
WhiletheBovineHDandBovineSNP50BeadChipsprovidesuperiorpowertointerrogategeneticvariationinhigh-valueanimalsandsupportgenome-widestudies,theBovineLDv2.0BeadChipenablesthecost-effectivegenotypingoflower-valueanimals.
HighImputationAccuracy
TheBeadChip’sstrategicallyselectedSNPspossessdemonstratedreliability,highaverageminorallelefrequency(MAF),uniformdistributionacrossthebovinegenome,andexcellentimputationperformanceforarangeofglobaldairybreeds.The7,931SNPsontheBovineLDv2.0BeadChipweresubjectedtorigorousfunctionaltestingonmultiplebreedstoensurestrongperformance.IlluminaensuresthateveryBovineLDBeadChipoffers>99%averagecallrateacrosscommondairyandbeefcattlebreeds.
Superior,ScalableContent
IlluminadevelopedtheBovineLDv2.0BeadChipaspartofaBovineLDConsortiumincollaborationwithglobalbovineagriculturalthoughtleaders.IlluminascientistsandcollaboratorsreferencedhistoricaldatageneratedwiththeBovineSNP50BeadChiptoidentifythebestSNPcontentforimputationefficiencyamongglobaldairybreeds.1
InsilicotestingdeterminedthatthehighestimputationefficiencycouldbeachievedbyoptimizingMAFamongtargetedbreedsandevenlyspacingSNPsacrosstheentirebovinegenomewithhighermarkerdensitiesatthechromosomalends.Contentincludescoverageofallchromosomes,includingX,knownYhaplotypes,andmitochondrialDNA.
High-ThroughputFormat
TheInfiniumAssaypowersthismulti-samplegenotypingpanel,deliveringtheindustry’shighestcallratesandreproducibility.Theassay’sPCR-freesingle-tubesamplepreparationsignificantlyreduceslaborandpotentialsamplehandlingerrors.2,3Amulti-sampleformatfurtherreducesexperimentalvariabilityandoverallprojectcostbyallowingbreederstointerrogateupto24samplesinparallel.
LearnMoreAboutPlantandAnimalGenotyping
Specifications:
| InputQuantity | 200ngDNA(at50ng/ul) |
| NumberofMarkers | Fixedmarkers:7931evenlyspacedSNPsacrossthegenomeu003cbru003eCustommarkeradd-oncapacity:Upto80,000(with+kitversions) |
| Technology | Microarray |
| SpeciesCategory | Bovine |
| AutomationCapability | LiquidHandlingRobots,Autoloader2.xArrayLoader |
| SystemCompatibility | iScan |
