NanoBright® Gold Nanoparticles:

NanoBright® gold nanoparticles from Nanocs have narrow size distribution yet with multiple size selection from 2 nm to 250 nm. These gold nanoparticles have spherical shape, completely soluble in water, have been used widely for the development of diagnostic probes, therapeutic agents and drug delivery vehicles. The optical and electronic properties of gold nanoparticles are tunable by changing the size, shape, surface chemistry and aggregate state. These gold nanoparticles can be further modified with different surface coatings and functional groups to render them with unique chemical and biological reactivity. Nanocs surface modified gold particles provide more choices for in-vitro or in-vivo applications of those nanoparticles. Customer conjugation and modification is available upon request.

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NanoBright® Gold Nanoparticle Properties:

• Orange, red or purple aqueous soution;
• Concentration: 0.01% (w/v) based on gold;

Gold nanoparticle Concentration and other properties:

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Particle Size (nm)	Particle Conc. (Particles/mL)	SPR Wavelength (nm)	Particle Size (nm)	Particle Conc. (Particles/mL)	SPR Wavelength (nm)
2	1.5x10E14	Not measured	40	9.0x10E10	~530
3	1.2x10E14	512~515	50	4.5x10E10	~535
5	5.0x10E13	515~520	60	3.1x10E10	~540
10	5.7x10E12	515~520	80	2.6x10E10	~553
15	1.4x10E12	517~522	100	1.1x10E10	~572
20	7.0x10E11	525	150	5.6x10E9	Not measured
30	2.0x10E11	527	200	1.7x10E9	Not measured

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Gold Nanoparticle Storage Conditions:

• Store at 4 ⁰C. DO NOT FREEZE.

Selected publications using Nanocs NanoBright® gold nanoparticles:

Hyungsoon Im et al, Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor. Nature Biotech 32, 490-495 (2014)

Yongkun Yang, Peter Burkhard: Encapsulation of gold nanoparticles into self-assembling protein nanoparticles. J of Nanobiotech 2012, 10:42.

Stacey L. et al. Protein-Ligand Binding Investigated by a Single Nanoparticle TERS Approach. Chem Commun 2011; 47(7): 2065–2067

Yoshiaki Maeda, et al, Noncovalent Immobilization of Streptavidin on In Vitro- and In Vivo-Biotinylated Bacterial Magnetic Particles. Appl. Environ. Microbiol. 2008 vol. 74 no. 16 5139-5145

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